{"id":7587,"date":"2023-12-21T15:26:05","date_gmt":"2023-12-21T14:26:05","guid":{"rendered":"https:\/\/www.sophim.com\/?p=7587"},"modified":"2024-02-01T18:11:58","modified_gmt":"2024-02-01T17:11:58","slug":"a-necessary-quality-control-for-the-cosmetic-industry","status":"publish","type":"post","link":"https:\/\/www.sophim.com\/en\/a-necessary-quality-control-for-the-cosmetic-industry\/","title":{"rendered":"A Necessary Quality Control for the Cosmetic Industry"},"content":{"rendered":"<h2>1. The Official Cosmetic Regulatory Bodies in France<\/h2>\n<p><span style=\"font-weight: 400;\">Unlike medications, cosmetic products do not require prior market authorization. Manufacturers must ensure that their products meet legislative and regulatory requirements and pose no health risks. <\/span><b>In France<\/b><span style=\"font-weight: 400;\">, two authorities have the power to oversee professionals in the cosmetic sector.<\/span><\/p>\n<h2><strong><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-7802 alignleft\" src=\"https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-1-300x300.jpg\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-1-300x300.jpg 300w, https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-1-1024x1024.jpg 1024w, https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-1-150x150.jpg 150w, https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-1-768x768.jpg 768w, https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-1.jpg 1080w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/strong><\/h2>\n<p><b>The ANSM <\/b><span style=\"font-weight: 400;\">(National Agency for the Safety of Medicines and Health Products) in France evaluates the toxicological profile of substances used in cosmetic products. Certain groups of substances, such as endocrine disruptors, receive special attention. This public institution also carries out a cosmetovigilance mission, monitoring adverse effects caused by cosmetic products. It relies on reports from healthcare professionals, industry players, and users.<\/span><\/p>\n<p><b>The DGCCRF <\/b><span style=\"font-weight: 400;\">(Directorate General for Competition Policy, Consumer Affairs, and Fraud Control) primarily verifies the legality of claims regarding the composition of cosmetic products. In 2020 and 2021, inspections conducted by the DGCCRF identified nearly a third of anomalies. Compliance requests focus particularly on:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The presence of unspecified allergens in the label, or the claim of &#8220;no major allergens&#8221; which can mislead consumers.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The presence of certain substances in the composition of products that claim not to contain them (for example, the presence of ethanol in a cosmetic product labeled \u201cethanol-free\u201d).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The absence of certain substances in the composition of products that claim to contain them (for example, a claim of aloe vera juice in a cosmetic product containing reconstituted aloe vera).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Claims of efficacy that cannot be proven, or which are not supported by clinical or scientific studies.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span class=\"button-custom\"><a href=\"https:\/\/www.sophim.com\/en\/cosmetics-european-regulations\/\">Discover other regulatory aspects of cosmetics<\/a><\/span><\/p>\n<h2><\/h2>\n<h2><\/h2>\n<h2>2. Indispensable quality control for all cosmetic companies<\/h2>\n<p><span style=\"font-weight: 400;\">The controls conducted by authorities do not replace the vigilance of companies. Regular quality controls are indispensable and address several major issues:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Comply with regulatory obligations in force on different national markets;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ensure the compliance and safety of ingredients used in the formulation of cosmetic products;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Provide a consistent level of quality across all batches produced and marketed, and maintain the standards that contribute to the brand&#8217;s reputation;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Support innovation, the definition of chemical structures, and the optimization of their production processes, and facilitate the approval of new raw materials.<\/span><\/li>\n<\/ul>\n<p><b>Several analytical methods<\/b><span style=\"font-weight: 400;\"> can be used to ensure some of these quality controls at all stages of the value chain.<\/span><\/p>\n<h3><span style=\"color: #6e9dd4;\"><strong>Chromatographic Techniques<\/strong><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Chromatography is a technique that allows the separation of chemical substances present in a homogeneous mixture, whether it is liquid or gaseous. It relies on the differences in behavior between a moving mobile phase and a stationary phase (also called a fixed phase). It is widely used in chemistry and biochemistry to separate, identify, and quantify the components of a sample.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Various chromatographic techniques can be employed in quality control.<\/span><\/p>\n<p><b><span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-7797 alignleft\" src=\"https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-300x300.jpg\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-300x300.jpg 300w, https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design-150x150.jpg 150w, https:\/\/www.sophim.com\/wp-content\/uploads\/2023\/12\/Untitled-design.jpg 540w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/span><\/b><\/p>\n<p>&nbsp;<\/p>\n<p><b>High-Performance Liquid Chromatography (HPLC)<\/b><span style=\"font-weight: 400;\"> separates the components of a mixture using a liquid as the mobile phase. The components move at different speeds through a column filled with a stationary substance, thus creating a separation based on their interactions with this substance.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Liquid-phase Ion Chromatography uses a column filled with an ion-exchange resin as the stationary phase. As the sample is transported through this column by a liquid phase, ions interact with the resin, resulting in their separation based on their charges and affinities for the resin.<\/span><\/p>\n<p><b>In Gas Chromatography<\/b><span style=\"font-weight: 400;\">, a gas is used as the mobile phase to move components through a column filled with a stationary substance. Components separate based on their volatility and interactions with the stationary substance, allowing precise analysis of different constituents in the mixture.<\/span><\/p>\n<p><b>Gel Permeation Chromatography (GPC)<\/b><span style=\"font-weight: 400;\"> or Size Exclusion Chromatography (SEC) relies on a column filled with porous gel beads as the stationary phase. Larger polymers are excluded from the pore network and pass more quickly through the column, while smaller polymers penetrate the pores and take longer to traverse the column. Thus, GPC\/SEC enables the classification of polymers based on their molecular weight.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"color: #6e9dd4;\"><strong>Spectrometry<\/strong><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">This technique <\/span><b>measures and analyzes the properties of electromagnetic radiation<\/b><span style=\"font-weight: 400;\"> emitted, absorbed, or scattered by matter. Spectrometry can identify components of a sample, determine their concentration, or provide information about their molecular structure. Several spectrometric techniques can be used for quality control in cosmetics.<\/span><\/p>\n<p><b>Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES)<\/b><span style=\"font-weight: 400;\"> uses a plasma induced by an induction coil to excite the atoms of elements in a liquid sample. This plasma generates characteristic light for each element, which is then analyzed by an optical spectrometer. By measuring the intensities of spectral lines emitted by the plasma, it becomes possible to identify different elements and quantify their concentration in the sample.<\/span><\/p>\n<p><b>UV-Vis Spectrometry <\/b><span style=\"font-weight: 400;\">uses a source of ultraviolet and visible light that passes through a sample. Molecules in the sample absorb light at specific wavelengths, generating an absorption spectrum. Analyzing this absorption at different wavelengths provides information about the presence and concentration of chemical components in the sample.<\/span><\/p>\n<p><b>In Fourier Transform Infrared Spectrometry (FTIR)<\/b><span style=\"font-weight: 400;\">, an infrared light beam passes through a sample. Molecules in the sample absorb specific amounts of infrared energy, causing molecular vibrations. A detector measures the light&#8217;s intensity after passing through the sample. Fourier Transform is then applied to convert these measurements into an infrared spectrum indicating the frequencies of molecular vibrations.<\/span><\/p>\n<h3><span style=\"color: #6e9dd4;\"><strong>Chemical and Physicochemical Analyses<\/strong><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Various chemical analyses are also used for quality control in cosmetics:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Acid-base titrations<\/b><span style=\"font-weight: 400;\"> determine the concentration of an acidic or basic substance in a solution.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Redox analysis <\/b><span style=\"font-weight: 400;\">measures the concentration of specific species in samples (atoms, molecules, ions, radicals, etc.).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Rheology <\/b><span style=\"font-weight: 400;\">studies the deformable behavior of matter and is particularly useful for studying the properties of a texture.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Particle size analysis <\/b><span style=\"font-weight: 400;\">characterizes the distribution of particle sizes in a solution.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3><span style=\"color: #6e9dd4;\"><strong>A Wide Range of Analyses for Quality Control<\/strong><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Other tests and analyses are regularly used to control the quality of a cosmetic product.<\/span><\/p>\n<p><b>Total Organic Carbon (TOC) technique<\/b><span style=\"font-weight: 400;\"> measures the total amount of carbon in a substance, whether it is in organic or inorganic form.<\/span><\/p>\n<p><b>Differential Scanning Calorimetry (DSC) <\/b><span style=\"font-weight: 400;\">measures heat changes associated with thermal transitions in a sample, characterizing the thermal properties of substances.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2>3. Rigorous Quality Control of Cosmetic Ingredients<\/h2>\n<p><span style=\"font-weight: 400;\">The quality of cosmetic products also relies on choosing partners and suppliers who share values and commitments to <\/span><b>good manufacturing practices<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">At SOPHIM, quality controls are assured throughout the process using robust analytical methods and high-performance equipment. Each batch of finished product is released only after all analyses are performed and if it conforms to pre-established specifications:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">5 Gas Chromatographs with FID detection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 Coulometric titrator for water microdosage: Karl Fischer method according to ASTM D 6304<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 Spectrocolorimeter for Gardner measurements according to ISO 4630 and Pt-Co ISO 6271<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 Digital densimeter for density measurements at different temperatures according to ISO 18301<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 Digital refractometer for refractive index measurements according to ISO 6320<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 Melting point measurement device by sliding according to ISO 6321<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 Titration equipment for saponification index measurements according to ISO 3657<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Sophim is also equipped with an OMNIS\u00ae automated titration robot (by METROHM) for potentiometric method dosages:<\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acid index according to ISO 660<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Peroxide index according to ISO 27107<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Iodine index according to ISO 3961<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span class=\"button-custom\"><a href=\"https:\/\/www.linkedin.com\/feed\/update\/urn:li:activity:7039155872945602560\/\">Watch the titration robot video on Linkedin<\/a><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sophim&#8217;s commitment to constant quality control is also reflected in the ISO 22716 certification. This certification commits to mastering the hazards and risks associated with cosmetic products and aims for continuous improvement throughout the supply chain, focusing on customer and partner satisfaction, and the end consumer.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For natural-origin cosmetic ingredients of consistent quality, contact your usual representative to access the catalog, call the teams at (+33)4 92 33 17 17, or send an online message.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. The Official Cosmetic Regulatory Bodies in France Unlike medications, cosmetic products do not require prior market authorization. Manufacturers must ensure that their products meet legislative and regulatory requirements and pose no health risks. In France, two authorities have the power to oversee professionals in the cosmetic sector. The ANSM (National Agency for the Safety [&hellip;]<\/p>\n","protected":false},"author":23,"featured_media":7588,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[55,19],"tags":[],"class_list":["post-7587","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-chemical-expertise","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Quality Control in the Cosmetics Industry | Sophim<\/title>\n<meta name=\"description\" content=\"Explore the importance of quality control in cosmetics, and the diverse procedures implemented by companies in the cosmetic industry.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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